Bronchorelaxent And Anti-Inflammatory Effect Of Heteropogon contortus (L.) Beauv. Methanolic Extract

Methanolic extract of Heteropogon contortus (L.) Beauv was screened for Bronchorelaxation (in vitro anti-histaminic) and in vivo anti-inflammatory effects. Bronchorelaxation effect was evaluated in terms of inhibition of histamine and acetylcholine induced contraction in guinea pig tracheal chain. Anti-inflammatory effect was assessed using carrageenan and egg albumin induced inflammation in rat paw edema model. HC-ME shown 24.02 percent inhibition of inflammation in carrageenan induced paw edema model at 200 mg/kg. At same dose extract inhibited 29.27 percent inflammation in egg albumin induced edema model. Percent bronchorelaxation exhibited by extract against histamine and acetylcholine induced contraction was found to be 40.63 and 45.81 respectively. While insignificant results were found in terms of bronchprotection effect of extract.